[2-(1-Piperidinylmethyl)phenyl]magnesium bromide
[2-(1-Piperidinylmethyl)phenyl]magnesium bromide
CAS: 480424-81-5
Molecular Formula: C6H4CH2NC5H10MgBr
[2-(1-Piperidinylmethyl)phenyl]magnesium bromide - Names and Identifiers
[2-(1-Piperidinylmethyl)phenyl]magnesium bromide - Physico-chemical Properties
| Molecular Formula | C6H4CH2NC5H10MgBr |
| Molar Mass | 278.47 |
| Density | 0.922g/mLat 25°C |
| Boling Point | 65°C |
| Flash Point | 1°F |
| Storage Condition | 2-8°C |
[2-(1-Piperidinylmethyl)phenyl]magnesium bromide - Risk and Safety
| Risk Codes | R11 - Highly Flammable R14 - Reacts violently with water R19 - May form explosive peroxides R34 - Causes burns R40 - Limited evidence of a carcinogenic effect R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S16 - Keep away from sources of ignition. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 2924 3/PG 2 |
| WGK Germany | 1 |
| HS Code | 29310099 |
[2-(1-Piperidinylmethyl)phenyl]magnesium bromide - Introduction
[2-(1-Piperidinylmethyl)phenyl]magnesium bromide is an organic magnesium reagent with the chemical formula C11H15BrMgN. The following are the properties, use, preparation and safety information of the compound:
Nature:
- [2-(1-Piperidinylmethyl)phenyl]magnesium bromide is a colorless to yellow crystalline solid.
-It is wettable at room temperature, can absorb moisture and react with water.
-It is stable to air and can be stored for a long time under an inert atmosphere.
-Its molecular weight is 301.38g/mol.
Use:
- [2-(1-Piperidinylmethyl)phenyl]magnesium bromide are commonly used as Grignard reagents in organic synthesis to introduce phenyl and piperidine groups in chemical reactions.
-It can react with aldehydes, ketones, carbonyl compounds, etc. to form C- C bonds.
-It can also participate in the synthesis of nitrogen heterocyclic compounds, such as pyrrole, thiophene, etc.
Preparation Method:
- [2-(1-Piperidinylmethyl)phenyl]magnesium bromide is usually prepared by reacting magnesium bromide with the corresponding bromophenyl compound in an inert solvent. The reaction conditions are generally low temperature and an inert atmosphere.
Safety Information:
- [2-(1-Piperidinylmethyl)phenyl]magnesium bromide is an organometallic reagent that needs to be handled carefully and used under suitable operating conditions.
-It may be irritating to the skin, eyes and respiratory tract, so proper personal protective equipment such as gloves, goggles and respiratory protection must be worn during operation.
-During operation, care should be taken to avoid contact with water and avoid the generation of flammable gases.
-When storing, it should be placed in a dry, cool, well-ventilated place, and away from oxidants and acids.
Please note: When using chemical reagents, it is important to follow safe practices and consult relevant literature and material safety data sheets for more comprehensive information.
Nature:
- [2-(1-Piperidinylmethyl)phenyl]magnesium bromide is a colorless to yellow crystalline solid.
-It is wettable at room temperature, can absorb moisture and react with water.
-It is stable to air and can be stored for a long time under an inert atmosphere.
-Its molecular weight is 301.38g/mol.
Use:
- [2-(1-Piperidinylmethyl)phenyl]magnesium bromide are commonly used as Grignard reagents in organic synthesis to introduce phenyl and piperidine groups in chemical reactions.
-It can react with aldehydes, ketones, carbonyl compounds, etc. to form C- C bonds.
-It can also participate in the synthesis of nitrogen heterocyclic compounds, such as pyrrole, thiophene, etc.
Preparation Method:
- [2-(1-Piperidinylmethyl)phenyl]magnesium bromide is usually prepared by reacting magnesium bromide with the corresponding bromophenyl compound in an inert solvent. The reaction conditions are generally low temperature and an inert atmosphere.
Safety Information:
- [2-(1-Piperidinylmethyl)phenyl]magnesium bromide is an organometallic reagent that needs to be handled carefully and used under suitable operating conditions.
-It may be irritating to the skin, eyes and respiratory tract, so proper personal protective equipment such as gloves, goggles and respiratory protection must be worn during operation.
-During operation, care should be taken to avoid contact with water and avoid the generation of flammable gases.
-When storing, it should be placed in a dry, cool, well-ventilated place, and away from oxidants and acids.
Please note: When using chemical reagents, it is important to follow safe practices and consult relevant literature and material safety data sheets for more comprehensive information.
Last Update：2024-04-10 22:29:15
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